“Trials on rats and rabbits (smaller animals) and monkeys (larger animals) proved successful. Phase I of the human clinical trials on 17 volunteers was completed in 1993. It went perfectly. Those who were injected Risug above a certain dosage were seen to possess no “viable sperm”; no side-effects were reported.
And then, someone photocopied sections from a book called Hazardous Chemicals: Desk Reference and sent them to the ICMR. The sections in question listed styrene and maleic anhydride, both part of Guha’s Risug formulation, as carcinogens. In response. Guha argued that substances can be individually toxic in nature but harmless as compounds. He gave the example of pure chlorine, which can melt human flesh on its own but, when combined with sodium, it becomes sodium chloride – the basic salt that we consume in our diets. But it wasn’t enough to persuade them.”